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CTP sensing and Mec1ATR-Rad53CHK1/CHK2 mediate a two-layered response to inhibition of glutamine metabolism

Name: CTP sensing and Mec1ATR-Rad53CHK1/CHK2 mediate a two-layered response to inhibition of glutamine metabolism
Creator: Christopher Bruhn
Published: 2026-04-09T12:26:18+08:00

Mendeley Data2026-04-09 收录

细胞代谢调控

DNA损伤响应

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Raw data for the manuscript "CTP sensing and Mec1ATR-Rad53CHK1/CHK2 mediate a two-layered response to inhibition of glutamine metabolism"

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Christopher Bruhn

DNA损伤响应

病毒-宿主相互作用蛋白质组学

HFF cells were infected with ICP0 RF HSV-1 (MOI 5), treated with bleomycin (10mg/mL), or left untreated as a control. Nu-7441 (DNA-PK inhibitor; 2uM)or DMSO (Control) was applied after 1 hour then sam

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Translational and transcriptional responses of fission yeast to MMS

DNA损伤响应

裂殖酵母基因表达

Translational and transcriptional responses of fission yeast to MMS

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Impact of transcriptional mutagenesis on p53 transactivation. Impact of transcriptional mutagenesis on p53 transactivation

p53转录调控

DNA损伤响应

The transcriptional error rate can be significantly increased by the presence of DNA lesions that instruct mis-insertion during transcription; a process referred to as transcriptional mutagenesis (TM)

NIAID Data Ecosystem30

The SOG1 transcriptional activator and the MyB3R family of repressors control a complex gene network in response to DNA damage in Arabidopsis [SOG1 ChIP-seq]

基因调控

DNA损伤响应

To combat DNA damage, organisms mount a DNA Damage Response (DDR) that results in cell cycle regulation, DNA repair, and, in severe cases, cell death. Underscoring the importance of gene regulation in

干细胞与再生医学数据中心2022-02-20 更新90

Growth-dependent heterogeneity in the DNA damage response in Escherichia coli

DNA损伤响应

单细胞分析

In natural environments bacteria are frequently exposed to sub-lethal levels of DNA damage which leads to the induction of a stress response (the SOS response in Escherichia coli). Natural environment

Scottish Government Open Data Portal2021-06-18 更新40

CTP sensing and Mec1ATR-Rad53CHK1/CHK2 mediate a two-layered response to inhibition of glutamine metabolism

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