Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a

This dataset contains the proposed sphingolipid rheostat model with mass-action kinetics and a proposed negative feedback from ceramide to its synthesis from Sphinganine. The model is written in the Systems Biology Markup Language (SBML) and with the experimental data, experimental conditions, parameters, and observables part of the PEtab paramter estimation problem. The PEtab problem was used to infer the parameters from the experimental data in a reproducible manner. It is uploaded with the scripts to execute the estimation and process the simulation results. Further, the estimated model parameters and model simulation results are uploaded in machine- and human-readable formats.