Rad52-inverse strand exchange drives RNA-templated DNA double-strand break repair. Mazina et al

NIAID Data Ecosystem2026-03-10 收录

DNA双链断裂修复

凝胶电泳图像

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https://data.mendeley.com/datasets/rkfwy7fvxc 数据链接链接失效反馈

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Images of unprocessed gels in main and supplementary figures.

创建时间：

2017-05-02

Human RECQ1 Interacts with Ku70/80 and Modulates DNA End-Joining of Double-Strand Breaks

DNA双链断裂修复

非同源末端连接

Genomic instability is a known precursor to cancer and aging. The RecQ helicases are a highly conserved family of DNA-unwinding enzymes that play key roles in maintaining genome stability in all livi

NIAID Data Ecosystem70

DMC1 ChIP-seq from B6xCAST F1 PRDM9-Humanized/CAST testes

减数分裂重组

DNA双链断裂修复

We report testis DMC1 enrichment at DSB (Double-Strand Break) hotspots in a B6xCAST F1 mouse, which is heterozygous at Prdm9, with one wild-type CAST allele and one allele found in human populations (

NIAID Data Ecosystem50

53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ

DNA双链断裂修复

免疫球蛋白类别转换重组

53BP1 governs a specialized, context-specific branch of the classical non-homologous end joining DNA double-strand break repair pathway. Mice lacking 53bp1 (also known as Trp53bp1) are immunodeficient

NIAID Data Ecosystem40

Cancer Cell Resistance to IFN? Can Occur via Enhanced Double-Strand Break Repair Pathway Activity [CRISPR screen]

癌症免疫治疗耐药性

DNA双链断裂修复

The pleiotropic cytokine interferon-gamma (IFN?) is known to be associated with cytostatic, anti-proliferation, and pro-apoptosis functions in cancer cells. However, cancer cells can become resistant

NIAID Data Ecosystem70

DEtail-seq profiled meiotic DSBs in Saccharomyces cerevisiae

减数分裂机制

DNA双链断裂修复

SPO11-promoted DNA double-strand breaks (DSBs) formation is a crucial step for meiotic recombination, and it is indispensable to detect the broken DNA ends accurately for dissecting the molecular mech

NIAID Data Ecosystem40

Rad52-inverse strand exchange drives RNA-templated DNA double-strand break repair. Mazina et al

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