Transcriptome sequencing of tumors with saline or LEGEND treatment

NIAID Data Ecosystem2026-03-14 收录

肿瘤微环境

药物转录组学

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA916759 数据链接链接失效反馈

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We evaluated the transcriptomic features of the tumor samples with saline or LEGEND treatment for investigating the TME modulation mechanism of LEGEND .

创建时间：

2022-12-29

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微生物共培养转录组

We studied how crosstalk with disseminated dormant breast cancer cells affects transcriptome of AT1-like cells and the requirement of EphB6 expression in the cancer cells for this genetic program Over

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Transcriptomic changes in a KRASG12C mutant cell line (H358 cells) treated with the allosteric SHP2 inhibitor TNO155 for different times

药物转录组学

KRAS突变肿瘤信号通路

Allosteric SHP2 inhibitors have been shown to be effective against RTKs and certain KRAS mutation-driven tumors in preclinical models. However, the comprehensive effects of SHP2 inhibitors on cellular

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Table_1_Comprehensive Genomic Characterization of Tumor Microenvironment and Relevant Signature in Clear Cell Renal Cell Carcinoma.xlsx

肿瘤微环境

基因组学

PurposeTo systematically investigate the characterization of tumor microenvironment (TME) in clear cell renal cell carcinoma (ccRCC), we performed a comprehensive analysis incorporating genomic altera

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DataSheet1_Poly I:C-priming of adipose-derived mesenchymal stromal cells promotes a pro-tumorigenic phenotype in an immunocompetent mouse model of prostate cancer.zip

肿瘤微环境

间充质基质细胞

Introduction: Mesenchymal stromal cells (MSC) are envisioned as a potential cellular vehicle for targeted cancer therapies due to their tumor tropism and immune permissiveness. An obstacle in their us

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Transcriptome sequencing of tumors with saline or LEGEND treatment

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