Precision Base Editing to Rescue LMNA Mutation-induced Cardiomyopathy-Xiaohui.pdf
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The efficient conversion of mutated A•T base pair to G•C using adenine base editors (ABEs) offers a promising therapeutic approach for genetic diseases, such as sickle cell disease progeria and cardiomyopathy. However, it remains unexplored whether ABE could effectively edit LMNA-DCM arising from specific G•C to A•T mutations.
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HRA Figshare创建时间：
2024-02-13
