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Asymmetry of STAT action in driving IL-27 and IL-6 transcriptional outputs and cytokine specificity

ChEBI2015-05-27 更新2026-07-12 收录

JAK-STAT信号通路

细胞因子调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-65621 数据链接链接失效反馈

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Asymmetry of STAT action in driving IL-27 and IL-6 transcriptional outputs and cytokine specificity

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创建时间：

2015-05-27

昆虫免疫响应

JAK-STAT信号通路

BackgroundThe Drosophila melanogaster gene CG11501 is up regulated after a septic injury and was proposed to act as a negative regulator of the JAK/STAT signaling pathway. Diedel, the CG11501 gene pro

NIAID Data Ecosystem80

Immunomodulatory activities of peptides IDR-HH2, IDR-1002 and IDR 1018 in human peripheral blood mononuclear cells (PBMC).

免疫调节肽

细胞因子调控

Cells were stimulated with 20 µg/ml of peptide. 1Experiments were performed 2–4 times and means are presented. All values for peptide treated cells represent significant induction relative to the untr

NIAID Data Ecosystem60

Partial TOR gene sequence

细胞因子调控

基因功能研究

To explore the molecular mechanism of TOR gene in promoting cell growth and overcoming host resistance

NIAID Data Ecosystem50

A Systems Biology approach to determine cell-specific gene regulatory effects of genetic associations in multiple sclerosis

多发性硬化症分子机制

细胞因子调控

We have conducted a cell-specific pathway analysis of the latest GWAS in multiple sclerosis (MS); which analyzed a total of 47,351 cases and 68,284 healthy controls and found more than 200 non-MHC gen

DataONE2019-09-17 更新70

Interleukin-6 Deficiency Influences Cytokine Expression in Susceptible BALB Mice Infected with Leishmania major but Does Not Alter the Outcome of Disease

感染免疫学

细胞因子调控

Since interleukin-6 (IL-6) may promote Th2 responses, we infected BALB IL-6-deficient (IL-6(−/−)) mice with Leishmania major. There was not a significant difference between the courses of infection (l

PubMed Central50

Asymmetry of STAT action in driving IL-27 and IL-6 transcriptional outputs and cytokine specificity

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