Signaling pathways that promote adipose tissue thermogenesis are well characterized, but the physiologic limiters of energy expenditure are largely unknown. Here we show that ablation of the anti-infl

干细胞与再生医学数据中心2022-02-20 更新70

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肝脏生物学

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数据集由实验室研究人员为探索Notch信号通路调控组织特化肝血窦内皮细胞表型及血管稳态而进行的多组测序。首先课题组构建并繁育了血管特异性Notch信号激活（Cdh5-Cre/NICD-OE）和Notch信号阻断（Cdh5-Cre/RBPj-KO）相关的转基因小鼠，通过基因型鉴定、诱导敲除，以实现血管特异性Notch信号改变，再通过磁珠分选获得纯化的肝血窦内皮细胞，进而进行转录组测序分析。通过分析我

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Additional file 1: of Inferring miRNA sponge co-regulation of protein-protein interactions in human breast cancer

乳腺癌分子机制

RNA调控网络

BRCA-related miRNA sponge interaction network. The network includes 37076 miRNA sponge interactions. (XLSX 484Â kb)

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Bao et al Dataset for NBME.xls

生物医学

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High-throughput screening of small molecules and proteins to identify signaling pathways that are important for human epicardial cell specification and self-renwal

DataCite Commons2020-09-03 更新60

Additional file 1: of Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion

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