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Regioselective Nitration of N‑Alkyl Anilines using tert-Butyl Nitrite under Mild Condition

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Figshare2018-12-21 更新2026-04-29 收录
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Regioselective ring nitration of N-alkyl anilines is reported using tert-butyl nitrite. The reactions proceed efficiently with a wide range of substrates providing synthetically useful N-nitroso N-alkyl nitroanilines in excellent yields which can be easily converted into N-alkyl phenylenediamines and N-alkyl nitroanilines using Zn-AcOH and HCl/MeOH, respectively.

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2018-12-21
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