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Clofazimine exposure in vitro selects efflux pump mutants and bedaquiline resistance

NIAID Data Ecosystem2026-05-26 收录

结核病耐药性

抗结核药物

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP163131 数据链接链接失效反馈

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资源简介：

A collection of 6 bedaquiline-resistant and 6 clofazimine-resistant spontaneous mutants isolated in vitro

应用场景：

创建时间：

2018-10-15

结核病耐药性

微生物基因组测序

WGS for drug-resistant strains mentioned in https://www.biorxiv.org/content/10.1101/2022.10.31.514625v1

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Mycobacterium tuberculosis identification and antibiotic resistance profiling using Nanopore sequencing

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纳米孔测序

TB seek is a new nanopore sequencing based test designed for simultaneous TB identification and antibiotic resistance genotyping. The TBseek test is based on multiplex PCR, targeting specific genes fo

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Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT416

结核病耐药性

结构生物学药物发现

Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT416 Descriptor: DIMETHYL SULFOXIDE, N,N-diethyl-2-[(8-fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl

Protein Data Bank Japan2023-10-11 更新40

Alao et al 2022 Trends in MTB Rifampicin Resistance in a tertiary Hospital in Nigeria

结核病耐药性

HIV共感染流行病学

A four-year data of 4,526 presumptive TB cases diagnosed using GeneXpert. Data included MTB cases, Rifampicin Resistance TBs and TB-HIV co-infection cases in a Nigerian Tertiary Hospital

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Transmitted Extended-spectrum XDR Tuberculosis in Beijing

结核病耐药性

基因组与表观基因组学

Drug-resistance to tuberculosis remains a major public health threat. Here, we report two cases of extended-spectrum XDR (XXDR) tuberculosis, resistant to most first and second-line agents. Correlatio

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Clofazimine exposure in vitro selects efflux pump mutants and bedaquiline resistance

资源简介：

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