P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway
收藏NIAID Data Ecosystem2026-05-01 收录
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资源简介：
We used RNA sequencing to deciphere a molecular basis for the synthethic lethality of non-genotoxic p53 activation and P-TEFb inhibition. Overall design: We treated HCT116 cell line in biological triplicates with DMSO, Nutlin-3a (10 uM), NVP-2 (20 nM), and Nutlin-3a (10 uM) together with NVP-2 (20 nM) for 8 hours.
创建时间：
2023-04-01
