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OCI-AML1-Cas9 EKO chemogenomic CRISPR screen. OCI-AML1-Cas9 EKO chemogenomic CRISPR screen

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NIAID Data Ecosystem2026-03-12 收录
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Identify genes that show synthetic lethal and synthetic recue interactions with chemical compounds Overall design: OCI-AML1-Cas9 EKO library cells were treated with compounds UM171 and DMSO as control for 14 days. Cells were pelleted every 2 days and DNA was extracted. ID sequences of the sgRNAs were amplified by PCR and the products were sent for sequencing in Illumina Nextseq500

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2020-09-01
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