Single cell and bulk TCR sequences - longitudinal study

NIAID Data Ecosystem2026-05-26 收录

T细胞受体序列分析

自身免疫疾病纵向追踪

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP102399 数据链接链接失效反馈

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资源简介：

descriptionAnalysis of TCR alpha and beta chains of single and bulk populations of antigen-specific T cells of celiac disease patients followed over time.

创建时间：

2018-12-31

Machine learning analysis of the T cell receptor repertoire identifies sequence features that predict self-reactivity. Machine learning analysis of the T cell receptor repertoire identifies sequence features that predict self-reactivity

T细胞受体序列分析

反应性预测

The T cell receptor (TCR) determines the specificity and affinity for both foreign and self-peptides presented by MHC. It is established that self-pMHC reactivity impacts T cell function, but it has b

NIAID Data Ecosystem70

Blood samples and associated clonotypes of publically available TCRβ sequences.

T细胞受体序列分析

免疫组库多样性

Male 1 (M1), Male 2 (M2) and Female 1 (F1). *Unseparated, memory and naïve samples 1 and 2 were taken one week apart. Descriptive statistics of the eight samples generated by [14]. This includes the n

NIAID Data Ecosystem40

DeepLION dataset information.

癌症早期检测

T细胞受体序列分析

For most cancers, early diagnosis and intervention can significantly improve cure rates and patient survival. Consequently, achieving early and accurate cancer detection has always been a central focu

Figshare2025-10-08 更新30

Summary of TCRβ CDR3 sequence data.

T细胞受体序列分析

免疫组库测序

The mean number of in-frame, read-through TCRβ CDR3 nucleotide sequence reads obtained from the CD8+CD45RO−CD45RAhiCD62L+ (naïve), CD8+CD45RO+CD45RAlow (memory), CD4+CD45RO−CD45RAhiCD62L+ (naïve) and

NIAID Data Ecosystem50

Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state. Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state

T细胞受体序列分析

T细胞分化

The T cell compartment must contain diversity in both T cell receptor (TCR) repertoire and cell state to provide effective immunity against pathogens. However, it remains unclear how differences in th

NIAID Data Ecosystem40

Single cell and bulk TCR sequences - longitudinal study

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