Fifth-wave Influenza A virus (H7N9) sequencing from risk assessment studies

The fifth-wave of the H7N9 influenza epidemic in China was distinguished by a sudden increase in human infections, an extended geographic distribution, and the emergence of highly pathogenic avian influenza (HPAI) viruses. This set of studies includes deep sequencing analysis of low pathogenic avian influenza (LPAI) and HPAI H7N9 human isolates from the fifth epidemic wave, in an assessment of their pathogenicity and transmissibility in mammalian models.