Germinal centers (GCs) are the primary site where B cells undergo affinity maturation, the process whereby the average affinity of antibodies increases with time after immunization.To investigate the
CSK bound to integrin alphaIIb beta3 negatively regulates SRC by phosphorylating the Tyr-530. Platelet adhesion to fibrinogen causes the disassociation of CSK from alphaIIb beta3 complex.
