Transcriptomic analysis of injured and uninjured knee joints from Trem2 KO mice [bulk RNA-seq]
收藏NIAID Data Ecosystem2026-03-14 收录
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资源简介：
Trem2 is a single-pass transmembrane receptor of the immunoglobulin superfamily and is primarily expressed in myeloid cells. Cells from injured and uninjured knee joints of wildtype C57BL/6 mice and Trem2 KO mice were sequenced to determine if Trem2 plays a role in macrophage differentiation or function after joint injury. Right knee joints of 10-week-old C57BL/6 and Trem2 KO mice were injured using a tibial compression injury model. Uninjured and 7-day post-injury joints were collected and cells were analyzed using bulk RNA-seq.
创建时间：
2022-10-17
