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Identification of anaplastic lymphoma kinase as a candidate of new therapeutic target for BCC

ChEBI2013-01-30 更新2026-07-21 收录

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分子靶点发现

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42109 数据链接链接失效反馈

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Identification of anaplastic lymphoma kinase as a candidate of new therapeutic target for BCC

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创建时间：

2013-01-30

癌症靶向治疗

siRNA基因沉默

Increased α-fetoprotein (AFP) levels have been reported to predict a poor prognosis in hepatocellular carcinoma (HCC). We assessed the mechanism of AFP involvement in the progression of HCC and determ

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Crystal structure of BRAF/MEK1 complex with NST-628 and an active RAF dimer

癌症靶向治疗

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Crystal structure of BRAF/MEK1 complex with NST-628 and an active RAF dimer Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dual specificity mitogen-activated protein kinase kina

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First-line targ veted therapies of advanced hepatocellular carcinoma: A Bayesian network analysis of randomized controlled trials

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药物疗效比较

Purpose A variety of targeted drug were developed and proved effective and safe in clinical trials. Our study aims to compare the efficacies and safety of different targeted drugs in advanced hepatoce

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Additional file 5 of Exploring an immune cells-related molecule in STEMI by bioinformatics analysis

急性心肌梗死免疫机制

分子靶点发现

Supplementary Material 5

Figshare2023-06-30 更新70

Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system

癌细胞重编程

癌症靶向治疗

Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

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Identification of anaplastic lymphoma kinase as a candidate of new therapeutic target for BCC

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