The multifaceted roles of the DNA polymerase subunit Pol32 in maintaining genome integrity

Alliance of Genome Resources2026-08-01 收录

基因组稳定性研究

酵母微阵列分析

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https://www.yeastgenome.org/dataset/GSE291566 数据链接链接失效反馈

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A total of 40 diploid WYpol32 strains that spontaneously produced red and white colonies were analyzed using a chromosome IV microarray.

3D genome organization, transcription and aberrant DNA replication contribute to genome instability at fragile sites

基因组稳定性研究

染色体脆弱位点分析

Common fragile sites (CFSs) are regions susceptible to replication stress and are hotspots for chromosomal instability in cancer. Several features characterizing CFSs have been associated with their i

NIAID Data Ecosystem50

Effects of oxidative stress on mitotic recombination and genomic stability in yeast after 20 passages. Effects of oxidative stress on mitotic recombination and genomic stability in yeast after 20 passages

基因组稳定性研究

DNA损伤修复机制

Oxidative stress is a common factor threatening genomic stability in almost all aerobic organisms. Using a yeast screening system, we measured the frequency of mitotic recombination was greatly elevat

NIAID Data Ecosystem40

Homo sapiens strain:Saos2 Genome sequencing. Homo sapiens strain:Saos2

基因组稳定性研究

细胞周期调控

We report that constitutive expression of p21(WAF1/Cip1), in a p53 loss of function environment, causes replication stress and triggers genomic instability by deregulating the replication licensing ma

NIAID Data Ecosystem30

Saccharomyces cerevisiae strain:delta|(-2)|-7B-YUNI300 Genome sequencing

基因组稳定性研究

DNA复制与修复

The present study was designed to answer three questions. First, do ribonucleotides incorporated during nuclear DNA replication in RER-defective yeast strains elevate the rate of loss-of-heterozygosit

NIAID Data Ecosystem40

Supplemental materials for macroH2A1 drives nucleosome dephasing and genome instability in histone-humanized yeast

染色质结构

基因组稳定性研究

Associated supplemental files for the study entitled "macroH2A1 drives nucleosome dephasing and genome instability in histone-humanized yeast". Files include the uncropped HiC maps and the reference g

Figshare2024-01-04 更新30

The multifaceted roles of the DNA polymerase subunit Pol32 in maintaining genome integrity

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