The GATA4 gene is transcribed to yield mRNA and the mRNA is translated to yield GATA4 protein (inferred from mouse homologs). MESP1 binds the promoter of the GATA4 gene and activates transcription (in
Using a systems biology approach, we discovered and dissected a three-way interaction between the immune system, the intestinal epithelium, and the microbiota. We found that mice lacking B lymphocytes
GATA4 is an essential transcription factor required for the development and function of multiple tissues, including a major role in gonadogenesis. Despite its crucial role, the molecular mechanisms th
GATA4 is a transcription factor known for its crucial role in the development of many tissues, including liver; however, its role in adult liver metabolism is unknown. Here, using high-throughput sequ