Assembly of Spirooxindole Derivatives via Organocatalytic Iminium-Enamine Cascade Reactions
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The assembly of complex spirocyclopentaneoxindoles via a novel organocatalytic iminium-enamine cascade process is reported. Reactions between 3-substituted oxindoles and α,β-unsaturated aldehydes catalyzed by second generation prolinol ethers provided the desired products in high yield with excellent levels of enantioselectivity in a single step.
创建时间：
2016-02-20
