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Enantioselective Synthesis of Polycyclic Indole Derivatives Based on aza-Morita–Baylis–Hillman Reaction

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NIAID Data Ecosystem2026-03-09 收录
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A chiral phosphine-catalyzed asymmetric aza-Morita–Baylis–Hillman reaction between indole-derived sulfonyl imines and bis­(3-chlorophenyl)­methyl acrylate has been developed, giving the desired adducts in good yields and enantiomeric excess values along with the further transformations to polycyclic indoles such as dihydropyrido­[1,2-a]­indole and dihydropyrazino­[1,2-a]­indole skeleton.

创建时间:
2016-02-12
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