Translocation breakpoints mapping and genomic features at the breakpoints.

NIAID Data Ecosystem2026-03-09 收录

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https://figshare.com/articles/dataset/Translocation_breakpoints_mapping_and_genomic_features_at_the_breakpoints_/3446870 数据链接链接失效反馈

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Translocation breakpoints mapping and genomic features at the breakpoints.

创建时间：

2016-11-01

Frequencies of translocation following creation of double-strand breaks by HO endonuclease during serial growth of wild type and mutant diploids a .

染色体易位

衰老遗传机制

aThe median translocation frequency was determined for each strain from at least 12 independent cultures. Fold differences from the median frequency obtained with the wild type strain with the same su

NIAID Data Ecosystem60

High-throughput genome-wide translocation sequencing in hormone receptor-positive breast cancer cell lines. Homo sapiens

染色体易位

激素受体阳性乳腺癌

Estrogen is a known risk factor for breast cancer development. In previous experimental studies, it is known as to induce DNA double-strand breaks in its transcriptional target regions. We studied if

NIAID Data Ecosystem50

Clinical features of carriers of reciprocal chromosomal translocations involving chromosome 2: report of nine cases and review of the literature

染色体易位

不育症

ABSTRACT Objective: To explore the clinical features of carriers of chromosome 2 translocations, enabling informed genetic counseling of these patients. Materials and Methods: Eighty-two male carriers

DataCite Commons2024-02-12 更新30

The Effect of Translocation-Induced Nuclear Re-organization on Gene Expression

染色体易位

基因表达调控

To study the effect of balanced chromosomal rearrangements on gene expression, we compared the transcriptomes of cell lines from control and t(11;22)(q23;q11) individuals. This translocation between c

NIAID Data Ecosystem50

High-throughput capture of cis-rearrangement and trans-rearrangement sequence [LAM-HTGTS]. High-throughput capture of cis-rearrangement and trans-rearrangement sequence [LAM-HTGTS]

替代末端连接修复

染色体易位

Cell cycle is a major determinant of DNA double-strand break (DSB) repair pathway choice with homologous recombination (HR) that is most active in S phase cells and non-homologous end-joining (NHEJ) t

NIAID Data Ecosystem50

Translocation breakpoints mapping and genomic features at the breakpoints.

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