In animals, events occurring early in life can have profound effects on subsequent life-history events. Early developmental stresses often produce negative long-lasting impacts, although positive effe
Characterization of functionally distinct Dendritic Cell (DC) subsets in mice has fueled interest in whether analogous counterparts exist in humans. Transcriptional modules of coordinately expressed g
To identify differences between keratinocytes (w/o Pp6) and dermal dendritic cells, epidermal or dermal cell suspensions from C57BL/6 mice or K5. Pp6fl/fl mice were subject to single-cell RNA-seq. Sin
Absence of Tet2 at mouse cells results in loss of hydroxymethylcytosine Overall design: Hydroxymethylmethylcytosine DNA immunoprecipitation sequencing (hMeDIP-seq) of mouse TET2 WT and KO GC B-cells