Family-based haplotype analysis between chromosome 9q21.32^* haplotypes and logACR among diabetic family members.

*9q21.32 haplotypes: rs1888747, rs1929547, and rs10868025. Haplotypes with estimated frequencies ≥0.01 are provided and were used to calculate global P-values. #Families = number of nuclear families informative for the HBAT analysis; a minimum of 5 informative families for each haplotype was required to compute global tests. S-E(S) = observed minus the expected transmission for each haplotype. Var(S) = variance of the observed transmission for each haplotype. Z score: positive values indicate risk haplotypes, negative values indicate protective haplotypes. Associations achieving nominal significance (P-value<0.05) are indicated in bold.