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siRNA Administration Against AFP Inhibits Hepatocellular Carcinoma Proliferation in Vitro and Progression in Mice

ChEBI2008-12-30 更新2026-07-21 收录

RNA干扰治疗

癌症靶向治疗

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-12307 数据链接链接失效反馈

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siRNA Administration Against AFP Inhibits Hepatocellular Carcinoma Proliferation in Vitro and Progression in Mice

应用场景：

创建时间：

2008-12-30

癌症靶向治疗

siRNA基因沉默

Increased α-fetoprotein (AFP) levels have been reported to predict a poor prognosis in hepatocellular carcinoma (HCC). We assessed the mechanism of AFP involvement in the progression of HCC and determ

NIAID Data Ecosystem80

Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system

癌细胞重编程

癌症靶向治疗

Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

NIAID Data Ecosystem60

First-line targ veted therapies of advanced hepatocellular carcinoma: A Bayesian network analysis of randomized controlled trials

癌症靶向治疗

药物疗效比较

Purpose A variety of targeted drug were developed and proved effective and safe in clinical trials. Our study aims to compare the efficacies and safety of different targeted drugs in advanced hepatoce

NIAID Data Ecosystem50

Crystal structure of BRAF/MEK1 complex with NST-628 and an active RAF dimer

癌症靶向治疗

RAS信号通路抑制

Crystal structure of BRAF/MEK1 complex with NST-628 and an active RAF dimer Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dual specificity mitogen-activated protein kinase kina

Protein Data Bank Japan2024-07-10 更新60

a broad range of SARS-CoV-2 inhibitor. Title: A siRNA targets and inhibits a broad range of SARS-CoV-2 infections including Delta variant

抗病毒药物研发

RNA干扰治疗

The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants has altered the trajectory of the COVID-19 pandemic and raised some uncertainty on long term efficiency of vaccin

NIAID Data Ecosystem50

siRNA Administration Against AFP Inhibits Hepatocellular Carcinoma Proliferation in Vitro and Progression in Mice

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