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Transcription profiling by high throughput sequencing of pancreatic beta cells from wild type and Abcc8 knockout mice
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创建时间：
2019-05-14
相关数据集
Transcriptional profiling of pancreatic beta cells from wild type and Abcc8 knock-out mice
Abcc8 (sulfonylurea receptor 1, SUR1) is an essential part of the ATP-sensitive potassium channel necessary for coupling energy metabolism and membrane potential. In this study we assessed the impact
NIAID Data Ecosystem80
Temporal Transcriptome Analysis of Pancreatic Ã-Cells in Response to Lipotoxicity and Glucolipotoxicity.
The pancreatic beta cell function failure is the core event of type 2 diabetes mellitus. High levels of free fatty acid and glucose are two main factor that induced pancreatic beta cell function failu
NIAID Data Ecosystem30
To investigate whether recover DNMT3A expression permitted adult beta cell of ÃRapKO establishing proper transcriptome
Murine islets were isolated from 8-week-old WT and ÃRapKO mice and initially recovered in 1640 RPMI supplemented with 10% serum, 11.1mM glucose overnight. Then islets were transfected with Lenti-GFP
NIAID Data Ecosystem00
Examination of gene expression in beta-cells isolated from either wildtype or alms1 mutant zebrafish
Examination of gene expression in beta-cells isolated from either wildtype or alms1 mutant zebrafish RNA-seq of beta-cells isolated from either wildtype or alms1 mutant zebrafish
NIAID Data Ecosystem80
Mus musculus domesticus Transcriptome or Gene expression. Mus musculus domesticus
mouse pancreatic beta cells were cultured in the presence glucose. RNA was extracted from cells and the transcriptome was profiled.
NIAID Data Ecosystem30
