The cost of DNA sequencing has been declined with an advancement of next generation sequencing. Throughput sequences of Illumina platform is larger than the other platforms, it has been tried to use f
We used both simulated and experimental datasets derived from human genomic DNA, human T cell receptor repertoires, and intra-host viral populations. Next, we summarize datasets shared here, i.e., D1,
While the importance of random sequencing errors decreases at higher DNA or RNA sequencing depths, systematic sequencing errors (SSEs) dominate at high sequencing depths and can be difficult to distin
We report the mutation profile of measles F gene by saturating mutagenesis. We evaluate the mutation rate of measles F gene in pCDNA3 backbone (shuttle plasmid), pEMC backbone (genome plasmid), and RT
The mutation rate is a fundamental evolutionary parameter with direct and appreciable effects on the health and function of individuals. In this project, we examine this important parameter in the dom
