首页/数据集/PANK3 plays a key role in preserving the integrity of the intestinal barrier in ulcerative colitis

PANK3 plays a key role in preserving the integrity of the intestinal barrier in ulcerative colitis

NIAID Data Ecosystem2026-05-02 收录

结肠炎机制

肠道屏障功能分子解析

数据链接：

https://data.mendeley.com/datasets/6pxssd7kpm 数据链接链接失效反馈

官方服务：

资源简介：

RNA-sequence data from the colonic tissue of AAV-PANK3-OE mice Metabolomic data from the serum and colon of DSS-treated mice

应用场景：

创建时间：

2025-06-27

肠道菌群失调

结肠炎机制

we found that deficiency of the E3 ligase Itch, which leads to spontaneous colitis and rectal prolapse, is associated with alteration of the gut microbiota. 16S rRNA sequencing showed expansion of col

NIAID Data Ecosystem80

DataSheet2_Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis.XLSX

结肠炎机制

生物标志物发现

Background: Ulcerative colitis (UC) is a disorder with unknown etiology, and animal models play an essential role in studying its molecular pathophysiology. Here, we aim to identify common conserved p

NIAID Data Ecosystem40

Data_Sheet_4_Lnc-ITSN1-2, Derived From RNA Sequencing, Correlates With Increased Disease Risk, Activity and Promotes CD4+ T Cell Activation, Proliferation and Th1/Th17 Cell Differentiation by Serving as a ceRNA for IL-23R via Sponging miR-125a in Inflammatory Bowel Disease.zip

结肠炎机制

Th17细胞调控

Background: This study aimed to investigate long-non-coding RNA (lncRNA) expression profiles and the correlation of lnc-ITSN1-2 expression with disease risk, activity and inflammation, and its influen

NIAID Data Ecosystem30

Gene Expression Profiling of Ulcerative Colitis

结肠炎机制

差异基因表达分析

Through laser capture microdissection and microarray analysis combined with slightly modified RNA extraction and amplification. we could analyze the subtle differential expression between colon norm

NIAID Data Ecosystem60

OTUD3 prevents ulcerative colitis by modulating microbiota-mediated STING activation

猪肠道免疫学

结肠炎机制

Human intestinal Thy1+ mesenchymal cells are considered as heterogeneous population. We performed single cell RNA sequencing (scRNA-seq) to characterize fibroblast populations in the colonic mucosa.Li

NIAID Data Ecosystem30

PANK3 plays a key role in preserving the integrity of the intestinal barrier in ulcerative colitis

资源简介：

相关数据集