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Rhodium-Catalyzed Addition–Cyclization of Hydrazines with Alkynes: Pyrazole Synthesis via Unexpected C–N Bond Cleavage

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NIAID Data Ecosystem2026-03-08 收录
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Rhodium-catalyzed addition–cyclization of hydrazines with alkynes has been achieved to afford highly substituted pyrazoles under mild conditions. The cascade reaction involves two transformations: addition of the C–N bond of hydrazines to alkynes via unexpected C–N bond cleavage and intramolecular dehydration cyclization.

创建时间:
2016-02-17
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