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Crystal structure of IBV 3CL protease (3CLpro) in complex with compound 8

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Protein Data Bank Japan2026-04-01 更新2026-05-23 收录
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Crystal structure of IBV 3CL protease (3CLpro) in complex with compound 8 Descriptor: (2~{S})-2-[[(2~{S})-3,3-dimethyl-2-[2,2,2-tris(fluoranyl)ethanoylamino]butanoyl]amino]-4-methyl-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]pentanamide, 3C-like proteinase Authors: Nie, T.Q, Su, H.X, Li, M.J, Xu, Y.C. Deposit date: 2025-04-26 Release date: 2025-12-24 Last modified: 2026-04-01 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure-Based Development of Ultra-Broad-Spectrum 3C-Like Protease Inhibitors. Adv Sci, 13, 2026

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2025-04-26
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