Fusion of RNAi hits and microarray expression changes improves pathway detection.

Table showing the number of genes-in-pathway associated with microarray DEG (upregulations), RNAi survival hits or fused gene lists in Kc167 cells treated with MMS. P-value of Fisher-exact test (one-tailed) comparison of the proportion of MMS altered/survival genes in each platform is also shown. “ND” (not-detected) means a given pathway was not detected or was not significantly enriched at a FDR<10%. Legend: “Total genes”: total number of genes in the reference pathway; “Microarray”: MMS-induced gene expressions; “RNAi screen”: MMS survival hits.