Crystal structure of STING CTD in complex with potent agonist D5

Crystal structure of STING CTD in complex with potent agonist D5 Descriptor: 4-[6-methoxy-5-[[6-methoxy-2-(4-oxidanyl-4-oxidanylidene-butanoyl)-1-benzothiophen-5-yl]sulfanylmethylsulfanyl]-1-benzothiophen-2-yl]-4-oxidanylidene-butanoic acid, Stimulator of interferon genes protein Authors: dos Reis, C.V, Hsu, N.-S, Rooney, T, Skidmore, J, Bernardes, G.J.L, Hyvonen, M. Deposit date: 2025-04-11 Release date: 2025-09-24 Last modified: 2025-12-10 Method: X-RAY DIFFRACTION (2.305 Å) Cite: Tumour-specific STING agonist synthesis via a two-component prodrug system. Nat.Chem., 17, 2025