Main effects of MMP genetic variants on clinical outcomes, all treatments combined.

CHD, coronary heart disease defined as fatal CHD or nonfatal myocardial infarction; CCHD, combined CHD defined as CHD death or non-fatal myocardial infarction plus revascularization procedures plus hospitalized angina; CCVD, combined cardiovascular disease defined as CHD death or non-fatal MI plus stroke, revascularization procedures, angina, heart failure, stroke, and peripheral arterial disease; ACM, all-cause mortality; CHF, .chronic heart failure.*adjusted for age, sex, race, Hispanic status, smoking status, diabetes status, aspirin use, and baseline values for BMI, SBP, DBP, HDL- and LDL-cholesterol.