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Multi-omics analysis of the biological mechanism of the pathogenesis of non-alcoholic fatty liver disease. Mus musculus

NIAID Data Ecosystem2026-05-01 收录

非酒精性脂肪性肝病机制

肝脏转录组

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1068522 数据链接链接失效反馈

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资源简介：

This set of data shows the results of liver transcriptome sequencing in mice with NAFLD and normal mice

应用场景：

创建时间：

2024-01-24

肝脏转录组

肠道菌群-宿主互作

Male C57BL/6J mice aged 3 weeks were randomly divided into 3 groups. (1) Control group: mice were given standard chow diet and gavaged with sterile PBS twice a week; (2) HFD group : mice were given hi

NIAID Data Ecosystem50

Transcriptomic analysis of liver of WT and p21KO mice upon 24h fasting

肝脏转录组

禁食代谢

We profiled total liver mRNA of WT and p21KO mice that were fed ad libitum or fasted for 24 hours 2-3 mice of each genotype were either fed or fasted for 24 hours, sacrificed and total mRNA was extra

Alliance of Genome Resources20

OXPHOS-Mediated Induction of NAD + Promotes Complete Oxidation of Fatty Acids and Interdicts Non-Alcoholic Fatty Liver Disease

非酒精性脂肪性肝病机制

脂肪酸代谢

OXPHOS is believed to play an important role in non-alcoholic fatty liver disease (NAFLD), however, precise mechanisms whereby OXPHOS influences lipid homeostasis are incompletely understood. We previ

NIAID Data Ecosystem20

High throughput RNA sequencing of hepatocellular carcinoma and pre tumor samples from Tdg fl/-; UBC-cre/ERT2+ mice livers and their age/sex matched Tdg fl/fl controls livers

肝脏转录组

癌症分子机制

We isolated whole livers from male TDG knockout livers (4-month post tamoxifen injection) and HCC, along with their age matched male control livers. RNA was extracted from the samples as per RNAzol m

NIAID Data Ecosystem30

Analysis of N6-methyladenosine Methylation Modification in Fructose-induced Non-alcoholic Fatty Liver Disease [MeRIP-Seq]

表观转录组学

非酒精性脂肪性肝病机制

Improvements in living standards have led to non-alcoholic fatty liver disease (NAFLD), one of the most common chronic liver diseases worldwide. Recent studies have shown that N6-methyladenosine (m6A)

NIAID Data Ecosystem20

Multi-omics analysis of the biological mechanism of the pathogenesis of non-alcoholic fatty liver disease. Mus musculus

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