Synthesis of Spiropentadiene Pyrazolones by Rh(III)-Catalyzed Formal sp<sup>3</sup> C–H Activation/Annulation
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资源简介：
A Rh-catalyzed enol-directed formal sp3 C–H activation/annulation of α-arylidene pyrazolones with alkynes has been developed. This reaction provides a convenient route to synthesize spiropentadiene pyrazolones in good to excellent yields at room temperature, exhibiting good functional group tolerance, gram scalability, and high regioselectivity. Of note, the α-arylidene pyrazolone was introduced as a novel C3 synthon in C–H activation/annulation.
创建时间：
2017-05-15
