Palladium-Catalyzed Domino Heck/Intermolecular C–H Bond Functionalization: Efficient Synthesis of Alkylated Polyfluoroarene Derivatives

An efficient palladium-catalyzed alkylation of electron-deficient polyfluoroarenes is described. The protocol provides a useful and operationally simple access to a broad scope of alkylated polyfluoroarene derivatives in moderate to excellent yields. This also represents the first example of the introduction of a polyfluoroarene structure involving an alkylpalladium­(II) intermediate.