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Transactivation-deficient p53 Mutants in Ras-induced Cellular Senescence

ChEBI2011-05-13 更新2026-07-21 收录

p53突变体功能

细胞衰老机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-27901 数据链接链接失效反馈

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资源简介：

Transactivation-deficient p53 Mutants in Ras-induced Cellular Senescence

应用场景：

创建时间：

2011-05-13

细胞衰老机制

血管内皮细胞基因表达

MicroRNAs regulate various cellular processes. While several genes associated with replicative senescence have been described in endothelial cells, miRNAs that regulate these genes remain largely unkn

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The epigenetic aspects of cellular responses to irradiation

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The project is aimed at the analysis of epigenetic effects of cellular responses to irradiation. Here we aim to sequence genomes, epigenomes, and transcriptomes of cells exposed to different kinds of

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Irreversibility of cellular aging and neoplastic transformation: a clonal analysis.

细胞衰老机制

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Prolonged incubation of NIH 3T3 cells under the growth constraint of confluence results in a persistent impairment of proliferation when the cells are subcultured at low density and a greatly increase

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Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

细胞衰老机制

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Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

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Supplementary Data 4 from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death

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p53突变体功能

p53 ChIPseq peaks from U2OS cells varying in p53 allelic status

Figshare2023-05-04 更新10