Directing an evolutionary trade-off in Salmonella via intestinal antibodies
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
A rationally induced IgA response blocking all of escape trajectories selected for Salmonella mutants carrying deletions of the O-antigen polymerase wzyB. Due to their short O-antigen, evolved mutants were susceptible to environmental stressors (detergents, complement), to predation (bacteriophages), and were impaired in gut colonization and virulence.
创建时间：
2021-04-07
