相关数据集
ADTRP条件敲除大鼠
通过与心肌特异的Cre大鼠杂交，从而获得心肌组织特异性敲除的ADTRP大鼠。通过超声影像（包括反映内径长度变化的参数左室收缩末期内径（LVEDD）及左室收缩末期内径（LVESD），反映后壁厚度的参数舒张末期左室后壁厚度（LVPWD）及收缩末期左室后壁厚度LVPWS，反映左室收缩功能的参数左室短轴缩短率（LVFS））和病理组织学（H&E染色显微水平和透射电镜超微水平）分析，在整体，显微和超微水平观察
中国科技资源共享网2026-07-12 更新170
小分子QF84139通过激活AMPK信号通路改善心肌肥厚
1，离体新生大鼠心肌细胞体系，苯肾上腺素诱导肥大模型，通过药物或基因操作处理，研究小分子化合物抗心肌肥厚作用与机制；2，野生型小鼠，主动脉弓狭窄手术构建压力超负荷心肌肥厚模型，通过药物处理，研究小分子化合物抗心肌肥厚作用；3，AMPKα2敲除小鼠，主动脉弓缩窄手术构建压力超负荷心肌肥厚模型，用于证明小分子作用机制
干细胞与再生医学数据中心2023-05-25 更新70
CircRNA sequencing in hypertrophic myocardium from abdominal aortic coarctation surgical mice
Pathological cardiac hypertrophy is a maladaptive cardiac remodeling in variable clinical diseases involving Hypertension, Cardiomyopathy and so on, which was still a major public healthcare problem w
Mendeley Data2024-04-30 更新50
Additional file 1 of Downregulation of salusins alleviates hypertrophic cardiomyopathy via attenuating oxidative stress and autophagy
Additional file 1: Figure S1. Levels of salusins after TOR2A downregulation. a Levels of salusin-α and salusin-β were reduced in the heart of rats after TOR2A knockdown. b Levels of salusin-α and salu
DataCite Commons2024-08-14 更新70
in vivo 3-day RNA Seq: vehicle, angiotensin II, and phenylephrine
To analyze Gq-receptor hypertrophic transcriptional profiles, 10 to 11 week old FVB/NJ mice were dosed at 30 mg/kg/day for phenylephrine and 0.5 mg/kg/day for angiotensin II using implanted micro-osmo
NIAID Data Ecosystem60
