Four-Component Domino Reaction Leading to Multifunctionalized Quinazolines

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Four-Component Domino Reaction Leading to Multifunctionalized Quinazolines

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2016-02-26

Mechanistic Insights into the B(C 6 F 5 ) 3 ‑Initiated Aldehyde–Aniline–Alkyne Reaction To Form Substituted Quinolines

多组分反应

喹啉衍生物

A substoichiometric quantity of the Lewis acid B(C6F5)3 is sufficient to initiate the aldehyde–amine–alkyne reaction, in a one-pot methodology that enables the synthesis of a range of functionalized

NIAID Data Ecosystem30

Gold-Catalyzed Addition– N ‑Boc Cleavage–Cyclization of N , O ‑Acetal with Ynamides for Construction of 6‑( tert -Butyldimethylsilyl)oxy-tetrahydropyrrolo[1,2‑ c ][1,3]oxazin-1-ones

催化有机合成

杂环化合物构建

A highly efficient gold-catalyzed approach between N,O-acetals and ynamides for the construction of 6-(tert-butyldimethylsilyl)oxy-tetrahydropyrrolo[1,2-c][1,3]oxazin-1-ones was developed. This re

NIAID Data Ecosystem30

Efficient Synthesis of Functionalized Benzo[ b ][1,8]naphthyridine Derivatives via Three-Component Reaction Catalyzed by l‑Proline

合成化学

多组分反应

A facile and efficient one-pot procedure for the preparation of functionalized benzo[b][1,8]naphthyridine derivatives by three-component reaction of 2-chloroquinoline-3-carbaldehyde, 1,3-dicarbonyl

NIAID Data Ecosystem20

Visible Light Photoredox Catalysis: Synthesis of Indazolo[2,3‑ a ]quinolines from 2‑(2-Nitrophenyl)-1,2,3,4-tetrahydroquinolines

有机合成光催化

杂环化合物构建

The synthesis of indazolo[2,3-a]quinoline derivatives in moderate to good yields from 2-(2-nitrophenyl)-1,2,3,4-tetrahydroquinolines via visible light photoredox catalysis is reported. The reaction in

NIAID Data Ecosystem30

A Concise Route to Pyridines from Hydrazides by Metal Carbene N−H Insertion, 1,2,4-Triazine Formation, and Diels−Alder Reaction

有机合成方法

杂环化合物构建

A simple, new three-step sequence for the conversion of hydrazides into pyridines is reported in which the key steps are N−H insertion by a copper carbene intermediate derived from α-diazo-β-ketoester

NIAID Data Ecosystem20

Four-Component Domino Reaction Leading to Multifunctionalized Quinazolines

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