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Efficient Synthesis of Functionalized Benzo[<i>b</i>][1,8]naphthyridine Derivatives via Three-Component Reaction Catalyzed by l‑Proline

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NIAID Data Ecosystem2026-03-08 收录
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A facile and efficient one-pot procedure for the preparation of functionalized benzo­[b]­[1,8]­naphthyridine derivatives by three-component reaction of 2-chloroquinoline-3-carbaldehyde, 1,3-dicarbonyl compounds, and enaminones catalyzed by l-proline is described. This new protocol has the advantages of environmental friendliness, good yields, and convenient operation.

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2014-05-12
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