Materials and methods, in depth description of the Topo II cycle, additional control experiments and the theoretical model. Additional figures, mainly regarding the characterization of the cantilever
Healthspan dataset summaries. Summaries of the three healthspan datasets (CeleST, heat stress, and oxidative stress) including information on the number of trials and animals, means, medians etc.
Mendelian randomization reveals an effect of lipid levels on DNA methylation for some of the EWAS-identified CpGs. Estimate is the percentage change in DNA methylation per standard deviation change in
