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Crystal structure of the human bromodomain of EP300 bound to the inhibitor XDM-CBP

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of the human bromodomain of EP300 bound to the inhibitor XDM-CBP Descriptor: 1,2-ETHANEDIOL, Histone acetyltransferase p300, ~{N}-[[2,8-bis(oxidanyl)naphthalen-1-yl]methyl]-4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrole-2-carboxamide Authors: Huegle, M, Wohlwend, D. Deposit date: 2017-04-28 Release date: 2017-08-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles. Angew. Chem. Int. Ed. Engl., 56, 2017

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2017-04-28
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