Crystal structure of PDE4D catalytic domain complexed with compound 21d
收藏Protein Data Bank Japan2023-11-29 更新2026-05-23 收录
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Crystal structure of PDE4D catalytic domain complexed with compound 21d Descriptor: 8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-9-oxidanyl-5-(pyridin-4-ylmethoxy)pyrano[3,2-b]xanthen-6-one, Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D, MAGNESIUM ION, ... Authors: Huang, Y.-Y, He, X, Luo, H.-B. Deposit date: 2022-03-17 Release date: 2023-02-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.100414 Å) Cite: Discovery of novel PDE4 inhibitors targeting the M-pocket from natural mangostanin with improved safety for the treatment of Inflammatory Bowel Diseases. Eur.J.Med.Chem., 242, 2022
创建时间：
2022-03-17
