Molecular bases of virulence variability in Staphylococcus aureus mastitis isolates
收藏官方服务：
资源简介：
Molecular bases of virulence variability in Staphylococcus aureus mastitis isolates
应用场景：
创建时间：
2011-11-11
相关数据集
Comparison of transcriptomic contents of a wild type Staphylococcus strain (HG001) and the spdC deleted derivative by RNAseq analysis.. Identification of SpdC regulated genes
We have characterized links between the SpdC protein and the WalKR two-component system. We have generated an spdC-deleted strain. This strain behaves like the WT parental strain, at least concerning
NIAID Data Ecosystem70
This study describes the target receptor and mechanism of action of Staphylococcal superantigen like 13 (SSL13), a secret protein reside on S.aureus immune evasion cluster 2(IEC-2) that previously supposed to modulate immune evasion. In sharp contrast to the characterized SSLs located on the staphylococcal pathogenicity island 2 (SPI-2) , that inhibit immune functions, We demonstrate SSL13 is a chemoattractant and a neutrophil activator that acts via the FPR2. Therefore, SSL13 is a unique SSL member not belonging to the immune evasion class, but is a pathogen alarming molecule sensed by the FPR2. Our study provides a new conception of SSLs, that not only inhibit host immune processes but also recruit human neutrophils to the site of infection, where S. aureus can be disarmed by secreted immune evasion proteins and used as vesicles to other parts of the host. This allow us to better understand of S. aureus pathological processes.
Staphylococcal Superantigen-Like (SSL) proteins, one of major virulence factor families produced by Staphylococcus aureus, were previously demonstrated to be immune evasion molecules that interfere wi
NIAID Data Ecosystem20
Transcriptome Comparison of staphylococcus aureus phoU Homologies: Genes Deletion strain and the Parent Strain in stationary phase (12 h)
Purpose: The goals of this study are to compare the wild type and phoU1 or phoU2 gene knock out transcriptome profiling (RNA-seq) to analysis gene expression change Methods: Samples was prepared acc
NIAID Data Ecosystem20
The SaeR/S Gene Regulatory System is Essential for Innate Immune Evasion by Staphylococcus aureus
Methicillin-resistant Staphylococcus aureus (MRSA) is problematic both in hospitals and the community. Currently, we have limited understanding of mechanisms of innate immune evasion used by S. aureus
NIAID Data Ecosystem60
Staphylococcus aureus strain:NSA | isolate:739 Genome sequencing. Staphylococcus aureus strain:NSA | isolate:739
Study of Helcococcus kunzii and Staphylococcus aureus interaction in an vitro chronic wound model. This sould highlight the role Helcococcus kunzii a commensal bacterium in the modulating the virulenc
NIAID Data Ecosystem20
