Staphylococcus aureus strain:NSA | isolate:739 Genome sequencing. Staphylococcus aureus strain:NSA | isolate:739

NIAID Data Ecosystem2026-05-01 收录

慢性伤口感染

金黄色葡萄球菌毒力

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1078120 数据链接链接失效反馈

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Study of Helcococcus kunzii and Staphylococcus aureus interaction in an vitro chronic wound model. This sould highlight the role Helcococcus kunzii a commensal bacterium in the modulating the virulence and pathogenecity of Staphylococcus aureus.

创建时间：

2024-02-20

Comparison of transcriptomic contents of a wild type Staphylococcus strain (HG001) and the spdC deleted derivative by RNAseq analysis.. Identification of SpdC regulated genes

金黄色葡萄球菌毒力

细菌双组分系统

We have characterized links between the SpdC protein and the WalKR two-component system. We have generated an spdC-deleted strain. This strain behaves like the WT parental strain, at least concerning

NIAID Data Ecosystem70

NarGHJI mediated virulence in Staphylococcus aureus

金黄色葡萄球菌毒力

RNA-seq差异表达分析

To investigate the function NarGHJI in the regulation of the expression of virulence factors, we constructed a narGHJI mutant by targeted deletion of narG in MRSA isolate USA300 LAC We then performed

NIAID Data Ecosystem30

This study describes the target receptor and mechanism of action of Staphylococcal superantigen like 13 (SSL13), a secret protein reside on S.aureus immune evasion cluster 2(IEC-2) that previously supposed to modulate immune evasion. In sharp contrast to the characterized SSLs located on the staphylococcal pathogenicity island 2 (SPI-2) , that inhibit immune functions, We demonstrate SSL13 is a chemoattractant and a neutrophil activator that acts via the FPR2. Therefore, SSL13 is a unique SSL member not belonging to the immune evasion class, but is a pathogen alarming molecule sensed by the FPR2. Our study provides a new conception of SSLs, that not only inhibit host immune processes but also recruit human neutrophils to the site of infection, where S. aureus can be disarmed by secreted immune evasion proteins and used as vesicles to other parts of the host. This allow us to better understand of S. aureus pathological processes.

金黄色葡萄球菌毒力

中性粒细胞免疫

Staphylococcal Superantigen-Like (SSL) proteins, one of major virulence factor families produced by Staphylococcus aureus, were previously demonstrated to be immune evasion molecules that interfere wi

NIAID Data Ecosystem20

The SaeR/S Gene Regulatory System is Essential for Innate Immune Evasion by Staphylococcus aureus

金黄色葡萄球菌毒力

先天免疫反应机制

Methicillin-resistant Staphylococcus aureus (MRSA) is problematic both in hospitals and the community. Currently, we have limited understanding of mechanisms of innate immune evasion used by S. aureus

NIAID Data Ecosystem60

Linking Virulence and Iron Limitation Response in Staphylococcus aureus: The sRNA IsrR Is Involved in SaeRS Activation

金黄色葡萄球菌毒力

铁限制响应机制

The Gram-positive opportunistic pathogen Staphylococcus aureus colonizes ∼30% of the human population but also causes various diseases. Precise regulation of genes involved in virulence and metabolic

NIAID Data Ecosystem30

Staphylococcus aureus strain:NSA | isolate:739 Genome sequencing. Staphylococcus aureus strain:NSA | isolate:739

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