The Menin–Bach2 axis is critical for regulating CD4 T cell senescence and homeostasis

ChEBI2014-03-27 更新2026-07-21 收录

T细胞免疫调节

细胞衰老机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-53831 数据链接链接失效反馈

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The Menin–Bach2 axis is critical for regulating CD4 T cell senescence and homeostasis

创建时间：

2014-03-27

Expression data from IMR90 cells expressing either E7-ca-STAT5A-shNTC vs E7-ca-STAT5a-shSOCS1 at 7 days post infection

细胞衰老机制

STAT信号通路

SOCS1 plays a role in cellular senescence. Knocking down SOCS1 in senescence induced by the STAT5 oncogene results in senescence bypass by preventing p53 activation IMR90 cells were infected with retr

NIAID Data Ecosystem80

Role of interleukin 2 on Foxp3+CD4+ regulatory T (Treg) cell gene expression and chromatin modeling in thymus and lymph node, and on SATB1 DNA binding in single positive CD4 thymocytes

T细胞免疫调节

表观基因组学

Interleukine 2 (IL-2) is still one of the most interesting cytokines in T cell biology with its ability to control immune homeostasis by maintaining the functional identity of Foxp3+ regulatory T (Tre

NIAID Data Ecosystem40

Gene regulatory basis of bystander activation in CD8+ T cells (human scRNA-seq). Gene regulatory basis of bystander activation in CD8+ T cells (human scRNA-seq)

T细胞免疫调节

单细胞转录组学

CD8+ T cells have been categorized as an adaptive lymphocyte, based on their ability to recognize specific foreign antigens and mount memory responses. However, neonatal and adult CD8+ T cells are der

NIAID Data Ecosystem30

Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

细胞衰老机制

肠道干细胞

Age-associated dysregulation of peroxisomal matrix protein importing impairs intestinal stem cell differentiation and gut functions

integrated proteome resources50

Control Mint-ChIP-seq from activated T-cell (ENCSR897COL)

表观遗传学分析

T细胞免疫调节

Control Mint-ChIP-seq on activated T-cell male adult (38 years) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENC

NIAID Data Ecosystem40

The Menin–Bach2 axis is critical for regulating CD4 T cell senescence and homeostasis

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