Human MST3 (STK24) kinase in complex with inhibitor MRLW5

Human MST3 (STK24) kinase in complex with inhibitor MRLW5 Descriptor: 1,2-ETHANEDIOL, 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one, Serine/threonine-protein kinase 24 Authors: Balourdas, D.I, Rak, M, Tesch, R, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) Deposit date: 2022-12-14 Release date: 2023-01-18 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Development of Selective Pyrido[2,3- d ]pyrimidin-7(8 H )-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors. J.Med.Chem., 67, 2024