Protein local synthesis at synapse is required for neuromuscular transmission

To profile the local translatome at the neuromuscular junction during various developmental stages We conducted RNA sequencing of synapse-enriched regions in the mouse diaphragms of both cre- and cre+ mice to investigate the local translatome at motor neuron terminals Comparative profiling analysis of RNA-seq data for ChAT-Cre positive and negative synapse-enriched diaphragms