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Additional file 1 of Interpreting drug synergy in breast cancer with deep learning using target-protein inhibition profiles

NIAID Data Ecosystem2026-05-01 收录

药物协同预测

癌症靶向治疗

数据链接：

https://figshare.com/articles/dataset/Additional_file_1_of_Interpreting_drug_synergy_in_breast_cancer_with_deep_learning_using_target-protein_inhibition_profiles/25322849 数据链接链接失效反馈

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资源简介：

Supplementary Material 1.

应用场景：

创建时间：

2024-02-29

癌症靶向治疗

RAS信号通路抑制

Crystal structure of BRAF/MEK1 complex with NST-628 and an active RAF dimer Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dual specificity mitogen-activated protein kinase kina

Protein Data Bank Japan2024-07-10 更新60

First-line targ veted therapies of advanced hepatocellular carcinoma: A Bayesian network analysis of randomized controlled trials

癌症靶向治疗

药物疗效比较

Purpose A variety of targeted drug were developed and proved effective and safe in clinical trials. Our study aims to compare the efficacies and safety of different targeted drugs in advanced hepatoce

NIAID Data Ecosystem50

Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule

癌症靶向治疗

基因表达谱分析

Human pancreatic ductal adenocarcinoma (PDAC) involves the dysregulation of multiple signalling pathways. A novel approach to the treatment of PDAC is described, involving the targeting of cancer gene

NIAID Data Ecosystem30

Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system

癌细胞重编程

癌症靶向治疗

Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

NIAID Data Ecosystem60

Best Fit Drug Response Parameters.

药物协同预测

放化疗优化

Cancer chemotherapy combines multiple drugs, but predicting the effects of drug combinations on cancer cell proliferation remains challenging, even for simple in vitro systems. We hypothesized that by

Figshare2023-05-01 更新30

Additional file 1 of Interpreting drug synergy in breast cancer with deep learning using target-protein inhibition profiles

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