KRAS-G12V in complex with BI-2865

KRAS-G12V in complex with BI-2865 Descriptor: (4S)-2-azanyl-4-methyl-4-[3-[4-[(1S)-1-[(2S)-1-methylpyrrolidin-1-ium-2-yl]ethoxy]pyrimidin-2-yl]-1,2,4-oxadiazol-5-yl]-6,7-dihydro-5H-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... Authors: Boettcher, J, Herdeis, L. Deposit date: 2022-09-06 Release date: 2023-06-21 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.02 Å) Cite: Pan-KRAS inhibitor disables oncogenic signalling and tumour growth. Nature, 619, 2023